Research in the Dmochowski lab encompasses many areas of Bioinorganic, Bioorganic, and Biophysical Chemistry, as well as Chemical Biology. Our lab is comprised of people with backgrounds spanning these disciplines. We are developing small molecules, proteins, and spectroscopic techniques for studying complex biomolecular systems. Our approach involves cycles of molecular design, synthesis, and measurement.
Wang, Y.; Roose, B. W.; Palovcak, E. J.; Carnevale, V.; Dmochowski, I. J. A Genetically Encoded β-Lactamase Reporter for Ultrasensitive 129 Xe NMR in Mammalian Cells. Angew. Chemie Int. Ed. 2016, 55 (31), 8984–8987.
Wang, Y.; Roose, B. W.; Philbin, J. P.; Doman, J. L.; Dmochowski, I. J. Programming A Molecular Relay for Ultrasensitive Biodetection through 129 Xe NMR. Angew. Chemie Int. Ed. 2016, 55 (5), 1733–1736.