Publications

2024

J.G. Marmorstein, V.V. Pagar, E. Hummingbird, I.G. Saleh, H.A.T. Phan, Y. Chang, K.D. Shaffer, Y. Venkatesh, I.J. Dmochowski, K.J. Stebe. Improved Large-Scale Synthesis of Acridonylalanine for Diverse Peptide and Protein Applications. Bioconjug. Chem., 2024. DOI: 10.1021/acs.bioconjchem.4c00411
G.B. Gomez-Dopazo, R.J. Agosto Nieves, R.L. Albarracín Rivera, S.M. Colon Morera, D.R. Nazario, I. Ramos, I.J. Dmochowski, D. Lee, V. Bansal. Cellulose Acetate Microwell Plates for High-Throughput Colorimetric Assays. RSC Adv., 2024, 14, 22, 15319–15327. DOI: 10.1039/d4ra01317d
S.A. Crane, F. Jiménez-Ángeles, Y. Wang, L.E. Ortuno Macias, J.G. Marmorstein, J. Deng, M. Molaei, E.J. Petersson, R. Radhakrishnan, C. De La Fuente-Nunez, M. Olvera De La Cruz, R.S. Tu, C. Maldarelli, I.J. Dmochowski, K.J. Stebe. Interfacial Rheology of Lanthanide Binding Peptide Surfactants at the Air–Water Interface. Soft Matter, 2024. DOI: 10.1039/d4sm00493k
Z. Zhao, N.A. Rudman, J., I.J. Dmochowski. A Site-Specific Cross-Linker for Visible Light Control of Proteins. ACS Omega, 2024, 9, 27, 29331-29338. DOI: 10.1021/acsomega/4c00968

2023

K. Du, I.J. Dmochowski. Thermally tunable adsorption of xenon in crystalline molecular sorbent. J. Phys. Chem. C, 2023. DOI: 10.1021/acs.jpcc.3c02054.

J. He, I.J. Dmochowski. Local xenon–protein interaction produces global conformational change and allosteric inhibition in lysozyme. Biochemistry, 2023, 62(11), 1659-1669. DOI: 10.1021/acs.biochem.3c00046

M.R. Herling, I.J. Dmochowski. Ratiometric, pH-sensitive probe for monitoring siRNA delivery. J. Am. Chem. Soc., 2023, 145(17), 9417-9422.

Z. Zhao, M. Zhou, S.D. Zemerov, R. Marmorstein, I.J. Dmochowski. Rational design of a genetically encoded NMR zinc sensor. Chem. Sci., 2023, 14, 3809-3815.

J.T. Shieh, J.A. Tintos-Hernandez, C.N. Murali, M.R. Penon Portmann, M. Flores-Mendez, A. Santana, J.A. Bolus, K. Du, L. Dupuis, N. Damseh, R. Mendoza-Londono, C. Berera, J.C. Lee, J.J. Phillips, C. APF Alves, I.J. Dmochowski, X.R. Ortiz-Gonzalez. Heterozygous nonsense variants in the ferritin heavy chain gene FTH1 cause a novel pediatric neuroferritinopathy. medRxiv, 2023.

Y. Lin, K. Du, M.R. Gau, I.J. Dmochowski. Turn-on fluorescent capsule for selective fluoride detection and water purification. Chem. Sci., 2023, 14, 291-297.

2022

J.C. Serrano, D. von Trentini, K.N. Berrios, A. Barka, I.J. Dmochowski, R.M. Kohli. Structure-guided design of a potent and specific inhibitor against the genomic mutator APOBEC3A. ACS Chem. Biol., 2022, 17(12), 3379-3388.

Z. Zhao, N.A. Rudman, J. He, I.J. Dmochowski. Programming xenon diffusion in maltose-binding protein. Biophys. J., 2022, 121(23), 4635-4643.

Y. Lin, M.R. Gau, P.J. Carroll, I.J. Dmochowski. Counteranions at Peripheral Sites Tune Guest Affinity for a Protonated Hemicryptophane. J. Org. Chem., 2022, 87(8), 5158-5165.

2021

J.A. Bulos, R. Guo, Z. Wang, M.A. DeLessio, J.G. Saven, I.J. Dmochowski. Design of a Superpositively Charged Enzyme: Human Carbonic Anhydrase II Variant with Ferritin Encapsulation and Immobilization. Biochemistry, 2021, 60(47). 3596-3609.

L. Yang, D. von Trentini, H. Kim, J.-Y. Sul, J.H. Eberwine, I.J. Dmochowski. Photoactivatable Circular Caged Oligonucleotides for Transcriptome In Vivo Analysis (TIVA). ChemPhotoChem, 2021, 5, 1-8.

L. Yang, I.J. Dmochowski. Conditionally Activated ("Caged") Oligonucleotides. Molecules, 2021, 26(5), 1481.

S.D. Zemerov, I.J. Dmochowski. Cryptophane-Xenon Complexes for ¹²⁹Xe MRI applications. RSC Adv., 2021, 11, 7693-7703.

S.D. Zemerov, Y. Lin, I.J. Dmochowski. Monomeric Cryptophane with Record-High Xe Affinity Gives Insights into Aggregation-Dependent Sensing. Anal. Chem., 2021, 93(3), 1507-1514.

2020

J.T. Shieh, A.J. Tintos-Hernandez, A. Santana, J.A. Bulos, C. Berera, J.J. Phillips, I.J. Dmochowski, X.R. Ortiz-Gonzalez. FTH1De Novo Dominant Variants Alter Iron Metabolism and Cause a Pediatric Onset Neuroferritinopathy. in Annals of Neurology, 2020, 88, S216.

S.B. Yeldell, L. Yang, J. Lee, J.H. Eberwine, I.J. Dmochowski. Oligonucleotide Probe for Transcriptome in Vivo Analysis (TIVA) of Single Neurons with Minimal Background. ACS Chem. Biol., 2020, 15(10), 2714-2721.

S.D. Zemerov, B.W. Roose, K.L. Farenhem, Z. Zhao, M.A. Stringer, A.R. Goldman, D.W. Speicher, I.J. Dmochowski. ¹²⁹Xe NMR-Protein Sensor Reveals Cellular Ribose Concentration. Anal. Chem., 2020, 92(19), 12817-12824.

K. Du, S.D. Zemerov, P.J. Carroll, I.J. Dmochowski. Paramagnetic Shifts and Guest Exchange Kinetics in Co_nFe_4-n Metal-Organic Capsules. Inorg. Chem., 2020, 59(17), 12758-12767.

L. Yang, J.H. Eberwine, I.J. Dmochowski. Caspase-Activated Oligonucleotide Probe. Bioconjugate Chem., 2020, 31(9), 2172-2178.

Z. Zhao, B.W. Roose, S.D. Zemerov, M.A. Stringer, I.J. Dmochowski. Detecting Protein-Protein Interactions by Xe-129 NMR. Chem. Commun., 2020, 56, 11122-11125.

K. Du, S.D. Zemerov, S. Hurtado Parra, J.M. Kikkawa, I.J. Dmochowski. Paramagnetic Organocobalt Capsule Revealing Xenon Host–Guest Chemistry. Inorg. Chem., 2020, 59(19), 13831-13844.

R. Chattaraj, M. Hwang, S.D. Zemerov, I.J. Dmochowski, D.A. Hammer, D. Lee, C.M. Sehgal. Ultrasound Responsive Noble Gas Microbubbles for Applications in Image‐Guided Gas Delivery. Adv. Healthcare Mater., 2020, 9, 1901721.

2019

T.L. Rapp, I.J. Dmochowski. Ruthenium-cross-linked hydrogels for rapid, visible-light protein release. Methods in enzymology, 624, 151-166, 2019.

T.L. Rapp, Y. Wang, M.A. Delessio, M.R. Gau, I.J. Dmochowski, Designing photolabile ruthenium polypyridyl crosslinkers for hydrogel formation and multiplexed, visible-light degradation, RSC Adv., 9, 4942-4947, 2019.

C.J. Ortiz, A.N. Santiago, A.J. Torres, J. Jiménez, S.B. Yeldell, R. Oyola, I.J. Dmochowski, J. Sotero-Esteva, V. Bansal, E. Fasoli, In situ analysis and imaging of aromatic amidine at varying ligand densities in solid phase, Anal. Bioanal. Chem., 411, 1549-1559, 2019.

2018

V.V. Shuvaev, M. Khoshnejad, K.W. Pulsipher, R.Y. Kiseleva, E. Arguiri, J.C. Cheung-Lau, K.M. LeFort, M. Christofidou-Solomidou, R.V. Stan, I.J. Dmochowski, V.R. Muzykantov, Spatially controlled assembly of affinity ligand and enzyme cargo enables targeting ferritinnanocarriers to caveolae, Biomaterials, 185, 348-359, 2018. DOI: 10.1016/j.biomaterials.2018.09.015

B.W. Roose, S.D. Zemerov, I.J. Dmochowski. Xenon–Protein Interactions: Characterization by X-Ray Crystallography and Hyper-CEST NMR. In Methods in enzymology, 602, 249-272, 2018. Academic Press. DOI: 10.1016/bs.mie.2018.02.005

B.W. Roose, S.D. Zemerov, Y. Wang, M. Kasimova, V. Carnevale, I.J. Dmochowski, A structural basis for Xe-129 Hyper-CEST signal in TEM-1 β-lactamase, ChemPhysChem, 19, 1-9, 2018. DOI: 10.1002/cphc.201800624. Cover feature. Highlighted in ChemistryViews.

K.W. Pulsipher, J.A. Bulos, J.A. Villegas, J.G. Saven, I.J. Dmochowski, A protein-protein host-guest complex: Thermostable ferritin encapsulatingpositively supercharged green fluorescent protein, Prot. Sci., 27, 1755-1766, 2018. PMID: 30051936, DOI: 10.1002/pro.3483

Zemerov, S.; Roose, B.; Greenberg, M.; Wang, Y.; Dmochowski, I. Cryptophane nanoscale assemblies expand Xe-129 NMR biosensing. Anal. Chem., 90(12), 7730-7738, 2018. PMCID: PMC6050516. DOI: 10.1021/acs.analchem.8b01630

Khoshnejad, M.; Parhiz, H.; Shuvaev, V.; Dmochowski, I.; Muzykantov, V. Ferritin-based drug delivery systems: hybrid nanocarriers for vascular immunotargeting. J. Control. Release, 282, 13-24, 2018. PMCID: PMC6008199. DOI: 10.1016/j.jconrel.2018.02.042

Yang, L.; Sul, J.-Y.; Kim, H.-B.; Yeldell, S.; Eberwine, J.; Dmochowski, I. Efficient synthesis of light-triggered circular antisense oligonucleotides targeting cellular protein expression. ChemBioChem, 19(12), 1250-1254, 2018. DOI: 10.1002/cbic.201800012

Khoshnejad, M.; Greineder, C.; Pulsipher, K.; Villa, C.; Altun, B.; Pan, D.; Tsourkas, A.; Dmochowski, I.; Muzykantov, V. Ferritin nanocarriers with biologically orthogonal conjugation for vascular targeting and imaging. Bioconjug. Chem., 29(4), 1209-1218, 2018. DOI: 10.1021/acs.bioconjchem.8b00004

Zhang, L.; Liang, D.; Wang, Y.; Gubu, A.; Yang, J.; Yu, L.; Dmochowski, I.; Tang, X. Circular siRNAs for reducing off-target effects and enhancing long-term gene silencing in cells and mice. Mol. Ther. Nucl. Acids, 10, 237-244, 2018. PMCID: PMC5768153 DOI: 10.1016/j.omtn.2017.12.007

T.L. Rapp, C.B. Highley, B. Manor, J.A. Burdick, I.J. Dmochowski, Ruthenium-crosslinked hydrogels with rapid, visible-light degradation, Chemistry-Eur. J., 24 (10), 2328-2333, 2018. PMCID: PMC5915374 DOI: 10.1002/chem.201704580

2017

Yeldell, S.; Ruble, B.; Dmochowski, I. Oligonucleotide modifications enhance probe stability for single cell transcriptome in vivo analysis (TIVA). Org. Biomol. Chem., 15, 10001-10009, 2017. DOI: 10.1039/C7OB02353G

Riggle, B. A.; Greenberg, M.; Wang, Y.; Wissner, R. F.; Zemerov, S.; Petersson, J.; Dmochowski, I. A cryptophane-based “turn-on” Xe-129 NMR biosensor for monitoring calmodulin. Org. Biomol. Chem., 15, 8883-8887, 2017. DOI: 10.1039/C7OB02391J

Roose, B. W.; Zemerov, S. D.; Dmochowski, I. J. Nanomolar small-molecule detection using a genetically encoded Xe-129 NMR contrast agent. Chem. Sci., 8, 7631-7636, 2017. DOI: 10.1039/C7SC03601A

Pulsipher, K. W.; Honig, S.; Deng, S.; Dmochowski, I. J. Controlling Gold Nanoparticle Seeded Growth in Thermophilic Ferritin Protein Templates. J. Inorg. Biochem., 174, 169-176, 2017. DOI: 10.1016/j.jinorgbio.2017.06.012

Pulsipher, K. W.; Villegas, J. A.; Roose, B. W.; Hicks, T. L.; Yoon, J.; Saven, J. G.; Dmochowski, I. J. Thermophilic Ferritin 24mer Assembly and Nanoparticle Encapsulation Modulated by Interdimer Electrostatic Repulsion. Biochemistry, 56(28), 3596-3606, 2017. DOI: 10.1021/acs.biochem.7b00296

Ping, J.; Pulsipher, K. W.; Vishnubhotla, R.; Villegas, J. A.; Hicks, T. L.; Honig, S.; Saven, J. G.; Dmochowski, I. J.; Johnson, A. T. C. Structural-Functional Analysis of Engineered Protein-Nanoparticle Assemblies Using Graphene Microelectrodes. Chem. Sci., 8, 5329-5334, 2017. DOI: 10.1039/C7SC01565H

2016

Wang, Y.; Dmochowski, I. J. An Expanded Palette of Xenon-129 NMR Biosensors. Acc. Chem. Res., 49(10), 2179-2187, 2016. DOI: 10.1021/acs.accounts.6b00309

Pulsipher, K. W.; Dmochowski, I. J. Ferritin: Versatile Host, Nanoreactor, and Delivery Agent. Isr. J. Chem., 56, 660-670, 2016. DOI: 10.1002/ijch.201600017

Wang, Y.; Roose, B. W.; Palovcak, E. J.; Carnevale, V.; Dmochowski, I. J. A Genetically Encoded ?-Lactamase Reporter for Ultrasensitive Xe-129 NMR in Mammalian Cells. Angew. Chem. Int. Ed., 55(31), 8984–8987, 2016. DOI: 10.1002/anie.201604055

Khoshnejad, M.; Shuvaev, V. V.; Pulsipher, K. W.; Dai, C.; Hood, E. D.; Arguiri, E.; Christofidou-Solomidou, M.; Dmochowski, I. J.; Greineder, C. F.; Muzykantov, V. R. Vascular Accessibility of Endothelial Targeted Ferritin Nanoparticles. Bioconjug. Chem., 27(3), 628-637, 2016. DOI: 10.1021/acs.bioconjchem.5b00641

Y. Wang, B.W. Roose, J.P. Philbin, J.L. Doman, I.J. Dmochowski. Programming a molecular relay for ultrasensitive biodetection by ¹²⁹Xe NMR. Angew. Chem. Int. Ed., 55(5), 1733-1736, 2016. DOI: 10.1002/anie.201508990

2015

Gao, L.; Liu, W.; Lee, O.-S.; Dmochowski, I. J.; Saven, J. G. Xe affinities of water-soluble cryptophanes and the role of confined water. Chem. Sci., 6(12), 7238–7248, 2016. DOI: 10.1039/C5SC02401C

Linganna, R. E.; Levy, W. J.; Dmochowski, I. J.; Eckenhoff, R. G.; Speck, R. M. Taxane modulation of anesthetic sensitivity in surgery for nonmetastatic breast cancer. J. Clin. Anesth., 27(6), 481–485, 2015. DOI: 10.1016/j.jclinane.2015.05.001

Ruble, B. K.; Yeldell, S. B.; Dmochowski, I. J. Caged oligonucleotides for studying biological systems. J. Inorg. Biochem., 150, 182-188, 2015. DOI: 10.1016/j.jinorgbio.2015.03.010

Wang, Y.; Dmochowski, I. J. Cucurbit[6]uril is an ultrasensitive Xe-129 NMR contrast agent. Chem. Commun., 51(43), 8982–8985, 2015. DOI: 10.1039/C5CC01826A

Riggle, B. A.; Wang, Y.; Dmochowski, I. J. A “Smart” Xe-129 NMR Biosensor for pH-Dependent Cell Labeling. J. Am. Chem. Soc., 137(16), 5542-5548, 2015. DOI: 10.1021/jacs.5b01938

Griepenburg, J. C.; Sood, N.; Vargo, K. B.; Williams, D.; Rawson, J.; Therien, M. J.; Hammer, D. A.; Dmochowski, I. J. Caging Metal Ions with Visible Light-Responsive Nanopolymersomes. Langmuir, 31(2), 799-807, 2015. DOI: 10.1021/la5036689

Griepenburg, J. C.; Rapp, T. L.; Carroll, P. J.; Eberwine, J.; Dmochowski, I. J. Ruthenium-caged antisense morpholinos for regulating gene expression in zebrafish embryos. Chem. Sci., 6, 2342–2346, 2015. DOI: 10.1039/C4SC03990D

Taratula, O.; Bai, Y.; D’Antonio, E. L.; Dmochowski, I. J. Enantiopure cryptophane-¹²⁹Xe nuclear magnetic resonance biosensors targeting carbonic anhydrase. Supramol. Chem., 27, 65-71, 2015. DOI: 10.108/10610278.2014.906601

2014

Khan, N. S.; Riggle, B. A.; Seward, G. K.; Bai, Y.; Dmochowski, I. J. Cryptophane-Folate Biosensor for Xe-129 NMR. Bioconjug. Chem., 26(1), 101-109, 2014. DOI: 10.1021/bc5005526

Bai, Y.; Wang, Y.; Goulian, M.; Driks, A.; Dmochowski, I. J. Bacterial spore detection and analysis using hyperpolarized ¹²⁹Xe chemical exchange saturation transfer (Hyper-CEST) NMR. Chem. Sci., 5(8), 3197-3203, 2014. DOI: 10.1039/C4SC01190B

Lovatt, D.; Ruble, B. K.; Lee, J.; Dueck, H.; Kim, T. K.; Fisher, S.; Francis, C.; Spaethling, J. M.; Wolf, J. a; Grady, M. S.; Ulyanova, A. V; Yeldell, S. B.; Griepenburg, J. C.; Buckley, P. T.; Kim, J.; Sul, J.-Y.; Dmochowski, I. J.; Eberwine, J. Transcriptome in vivo analysis (TIVA) of spatially defined single cells in live tissue. Nat. Methods, 11, 190-196, 2014. DOI: 10.1038/nmeth.2804

Cheung-Lau, J. C.; Liu, D.; Pulsipher, K. W.; Liu, W.; Dmochowski, I. J. Engineering a well-ordered, functional protein-gold nanoparticle assembly. J. Inorg. Biochem., 130, 59-68, 2014. DOI: 10.1016/j.jinorgbio.2013.10.003

2013

Liao, Z.; Hsieh, W.-T.; Baumgart, T.; Dmochowski, I.J.; Measuring interactions between polydimethylsiloxane and serum proteins at the air-water interface. Langmuir, 29(30), 9420-9427, 2013. DOI: 10.1021/la401619s

Griepenburg, J. C.; Ruble, B. K.; Dmochowski, I. J., Caged oligonucleotides for bidirectional photomodulation of let-7 miRNA in zebrafish embryos. Bioorg. Med. Chem., 21(20), 6198-6204. DOI: 10.1016/j.bmc.2013.04.082

Emerson, D. J.; Weiser, B. P.; Psonis, J.; Liao, Z.; Taratula, O.; Fiamengo, A.; Wang, X.; Sugasawa, K.; Smith Iii, A. B.; Eckenhoff, R. G.; Dmochowski, I. J., Direct modulation of microtubule stability contributes to anthracene general anesthesia. J. Am. Chem. Soc., 135(14), 5289-5398, 2013. DOI: 10.1021/ja311171u

2012

Bai, Y.; Hill, P. A.; Dmochowski, I. J., Utilizing a water-soluble cryptophane with fast xenon exchange rates for picomolar sensitivity NMR measurements. Anal. Chem., 84(22), 9935-9941, 2012. DOI: 10.1021/ac302347y

Laureano-Perez, L.; Colle, R.; Jacobson, D. R.; Fitzgerald, R.; Khan, N. S.; Dmochowski, I. J., A novel application for Rn-222 emanation standards: Radon-cryptophane host chemistry. Appl. Radiat. Isot., 70(9), 1997-2001, 2012. DOI: 10.1016/j.apradiso.2012.02.099

Taratula, O.; Kim, M. P.; Bai, Y.; Philbin, J. P.; Riggle, B. A.; Haase, D. N.; Dmochowski, I. J., Synthesis of enantiopure, trisubstituted cryptophane-A derivatives. Org. Lett., 14(14), 3580-3583, 2012. DOI: 10.1021/ol300943w

Emerson, D. J.; Liao, Z.; Eckenhoff, R. G.; Dmochowski, I. J., A novel fluorescent general anesthetic enables imaging of sites of action in vivo. Anesthesiology, 116(6), 1363. DOI: 10.1097/ALN.0b013e31824cb4b1

Bu, W.; Liu, R.; Cheung-Lau, J. C.; Dmochowski, I. J.; Loll, P. J.; Eckenhoff, R. G., Ferritin couples iron and fatty acid metabolism. FASEB Journal, 26(6), 2394-2400, 2012. DOI: 10.1096/fj.11-198853

Liu, R.; Bu, W.; Xi, J.; Mortazavi, S. R.; Cheung-Lau, J. C.; Dmochowski, I. J.; Loll, P. J., Beyond the detergent effect: A binding site for sodium dodecyl sulfate (SDS) in mammalian apoferritin. Acta Crystallographica Section D: Biological Crystallography, 68(5), 497-504, 2012. DOI: 10.1107/S0907444912002740

Ruble, B. K.; Richards, J. L.; Cheung-Lau, J. C.; Dmochowski, I. J., Mismatch discrimination and efficient photomodulation with split 10-23 DNAzymes. Inorg. Chim. Acta, 380(1), 386-391, 2012. DOI: 10.1016/j.ica.2011.10.068

2011 and Before

Liao, Z.; Lampe, J. W.; Ayyaswamy, P. S.; Eckmann, D. M.; Dmochowski, I. J., Protein assembly at the air-water interface studied by fluorescence microscopy. Langmuir, 27(21), 12775-12781, 2011. DOI: 10.1021/la203053g
Kamat, N. P.; Liao, Z.; Moses, L. E.; Rawson, J.; Therien, M. J.; Dmochowski, I. J.; Hamme, D. A., Sensing membrane stress with near IR-emissive porphyrins. Proc. Natl. Acad. Sci. U.S.A., 108(34), 13984-13989, 2011. DOI: 10.1073/pnas.1102125108
Jacobson, D. R.; Khan, N. S.; Colle, R.; Fitzgerald, R.; Laureano-Perez, L.; Bai, Y.; Dmochowski, I. J., Measurement of radon and xenon binding to a cryptophane molecular host. Proc. Natl. Acad. Sci. U.S.A., 108(27), 10969-10973, 2011. DOI: 10.1073/pnas.1105227108
Seward, G. K.; Bai, Y.; Khan, N. S.; Dmochowski, I. J., Cell-compatible, integrin-targeted cryptophane-Xe-129 NMR biosensors. Chem. Sci., 2(6), 1103-1110, 2011. DOI: 10.1039/c1sc00041a
Taratula, O.; Hill, P. A.; Bai, Y.; Khan, N. S.; Dmochowski, I. J., Shorter synthesis of trifunctionalized cryptophane - A derivatives. Org. Lett., 13(6), 1414-1417, 2011. DOI: 10.1021/ol200088f
Khan, N. S.; Perez-Aguilar, J. M.; Kaufmann, T.; Hill, P. A.; Taratula, O.; Lee, O. S.; Carroll, P. J.; Saven, J. G.; Dmochowski, I. J., Multiple hindered rotators in a gyroscope-inspired tribenzylamine hemicryptophane. J. Org. Chem., 76(5), 1418-1424, 2011. DOI: 10.1021/jo102480s
Taratula, O.; Hill, P. A.; Khan, N. S.; Carroll, P. J.; Dmochowski, I. J., Crystallographic observation of 'induced fit' in a cryptophane host-guest model system. Nat. Commun., 1, 2010. DOI: 10.1038/ncomms1151
Kamat, N. P.; Robbins, G. P.; Rawson, J.; Therien, M. J.; Dmochowski, I. J.; Hammer, D. A., A generalized system for photoresponsive membrane rupture in polymersomes. Adv. Funct. Mater., 20(16), 2588-2596, 2010. DOI: 10.1002/adfm.201000659
Lampe, J. W.; Liao, Z.; Dmochowski, I. J.; Ayyaswamy, P. S.; Eckmann, D. M., Imaging macromolecular interactions at an interface. Langmuir, 26(4), 2452-2459, 2010. DOI: 10.1021/la903703u
Richards, J. L.; Seward, G. K.; Wang, Y. H.; Dmochowski, I. J., Turning the 10-23 DNAzyme on and off with light. ChemBioChem, 11(3), 320-324, 2010. DOI: 10.1002/cbic.200900702
Taratula, O.; Dmochowski, I. J., Functionalized Xe-129 contrast agents for magnetic resonance imaging. Curr. Opin. Chem. Biol., 14(1), 97-104, 2010. DOI: 10.1016/j.cbpa.2009.10.009
Dmochowski, I., Xenon out of its shell. Nat. Chem., 1(3), 250, 2009. DOI: 10.1038/nchem.230
Swift, J.; Butts, C. A.; Cheung-Lau, J.; Yerubandi, V.; Dmochowski, I. J., Efficient Self-Assembly of Archaeoglobus fulgidus ferritin around metallic cores. Langmuir, 25(9), 5219-5225, 2009. DOI: 10.1021/la8040743
Butts, C. A.; Xi, J.; Brannigan, G.; Saad, A. A.; Venkatachalan, S. P.; Pearce, R. A.; Klein, M. L.; Eckenhoff, R. G.; Dmochowski, I. J., Identification of a fluorescent general anesthetic, 1-aminoanthracene. Proc. Natl. Acad. Sci. U.S.A., 106(16), 6501-6506. DOI: 10.1073/pnas.0810590106
Robbins, G. P.; Jimbo, M.; Swift, J.; Therien, M. J.; Hammer, D. A.; Dmochowski, I. J., Photoinitiated destruction of composite Porphyrin-Protein polymersomes. J. Am. Chem. Soc., 131(11), 3872-3874, 2009. DOI: 10.1021/ja808586q
Aru Hill, P.; Wei, Q.; Troxler, T.; Dmochowski, I. J., Substituent effects on xenon binding affinity and solution behaviour of water-soluble cryptophanes. J. Am. Chem. Soc., 131(8), 3069-3077, 2009. DOI: 10.1021/ja8100566
Chambers, J. M.; Hill, P. A.; Aaron, J. A.; Han, Z.; Christiansen, D. W.; Kuzma, N. N.; Dmochowski, I. J., Cryptophane xenon-129 nuclear magnetic resonance biosensors targeting human carbonic anhydrase. J. Am. Chem. Soc., 131(2), 563-569. DOI: 10.1021/ja806092w
Butts, C. A.; Swift, J.; Kang, S. G.; Di Costanzo, L.; Christiansen, D. W.; Saven, J. G.; Dmochowski, I. J., Directing noble metal ion chemistry within a designed ferritin protein. Biochemistry, 47(48), 12729-12739, 2008. DOI: 10.1021/bi8016735
Richards, J. L.; Tang, X.; Turetsky, A.; Dmochowski, I. J., RNA bandages for photoregulating in vitro protein synthesis. Bioorg. Med. Chem. Lett., 18(23), 6255-6258. DOI: 10.1016/j.bmcl.2008.09.093
Seward, G. K.; Wei, Q.; Dmochowski, I. J., Peptide-mediated cellular uptake of cryptophane. Bioconjug. Chem., 19(11), 2129-2135, 2008. DOI: 10.1021/bc8002265
Aaron, J. A.; Chambers, J. M.; Jude, K. M.; Di Costanzo, L.; Dmochowski, I. J.; Christianson, D. W., Structure of a 129Xe-cryptophane biosensor complexed with human carbonic anhydrase II. J. Am. Chem. Soc., 130(22), 6942-6943, 2008. DOI: 10.1021/ja802214x
Tang, X.; Swaminathan, J.; Gewirtz, A. M.; Dmochowski, I. J., Regulating gene expression in human leukemia cells using light-activated oligodeoxynucleotides. Nucleic Acids Res., 36(2), 559-569, 2008. DOI: 10.1093/nar/gkm1029
Zhang, L.; Swift, J.; Butts, C. A.; Yerubandi, V.; Dmochowski, I. J., Structure and activity of apoferritin-stabilized gold nanoparticles. J. Inorg. Biochem., 101(11-12), 1719-1729, 2007. DOI: 10.1016/j.jinorgbio.2007.07.023
Hill, P. A.; Wei, Q.; Eckenhoff, R. G.; Dmochowski, I. J., Erratum: Thermodynamics of xenon binding to cryptophane in water and human plasma (Journal of the American Chemical Society (2007) 129, (9262-9263)). J. Am. Chem. Soc., 129(37), 11662. DOI: 10.1021/ja075845q
Tang, X.; Maegawa, S.; Weinberg, E. S.; Dmochowski, I. J., Regulating gene expression in zebrafish embryos using light-activated, negatively charged peptide nucleic acids. J. Am. Chem. Soc., 129(36), 11000-11001, 2007. DOI: 10.1021/ja073723s
Hill, P. A.; Wei, Q.; Eckenhoff, R. G.; Dmochowski, I. J., Thermodynamics of xenon binding to cryptophane in water and human plasma. J. Am. Chem. Soc., 129(30), 9262-9263, 2007. DOI: 10.1021/ja072965p
Dmochowski, I. J.; Tang, X., Taking control of gene expression with light-activated oligonucleotides. BioTechniques, 43(2), 161-171, 2007. DOI: 10.2144/000112519
Dmochowski, I.; Tang, X., Probing expression. Org. Biomol. Chem., 5(3), 2007. DOI: 10.1039/C3OB41467A
Tang, X.; Dmochowski, I. J., Regulating gene expression with light-activated oligonucleotides. Mol. BioSyst., 3(2), 100-110, 2007. DOI: 10.1039/b614349k
Tang, X. J.; Dmochowski, I. J., Synthesis of light-activated antisense oligodeoxynucleotide. Nat. Protoc., 1(6), 3041-3048, 2007. DOI: 10.1038/nprot.2006.462
Wei, Q.; Seward, G. K.; Hill, P. A.; Patton, B.; Dimitrov, I. E.; Kuzma, N. N.; Dmochowski, I. J., Designing Xe-129 NMR biosensors for matrix metalloproteinase detection. J. Am. Chem. Soc., 128(40), 13274-13283, 2006. DOI: 10.1021/ja0640501
Swift, J.; Wehbi, W. A.; Kelly, B. D.; Stowell, X. F.; Saven, J. G.; Dmochowski, I. J., Design of functional ferritin-like proteins with hydrophobic cavities. J. Am. Chem. Soc., 128(20), 6611-6619, 2006. DOI: 10.1021/ja057069x
Tang, X.; Dmochowski, I. J., Controlling RNA digestion by RNase H with a light-activated DNA hairpin. Angew. Chem. Int. Ed., 45(21), 3523-3526, 2006. DOI: 10.1002/anie.200600954
Agadjanian, H.; Weaver, J. J.; Mahammed, A.; Rentsendorj, A.; Bass, S.; Kim, J.; Dmochowski, I. J.; Margalit, R.; Gray, H. B.; Gross, Z.; Medina-Kauwe, L. K., Specific delivery of corroles to cells via noncovalent conjugates with viral proteins. Pharm. Res., 23(2), 367-377, 2006. DOI: 10.1007/s11095-005-9225-1
Tang, X.; Richards, J. L.; Peritz, A. E.; Dmochowski, I. J., Photoregulation of DNA polymerase I (Klenow) with caged fluorescent oligodeoxynucleotides. Bioorg. Med. Chem. Lett., 15(23), 5303-5306, 2005. DOI: 10.1016/j.bmcl.2005.08.058
Tang, X.; Dmochowski, I. J., Phototriggering of caged fluorescent oligodeoxynucleotides. Org. Lett., 7(2), 279-282, 2005. DOI: 10.1021/ol047729n
Arnone, M. I.; Dmochowski, I. J.; Gache, C., Using reporter genes to study cis-regulatory elements. Methods Cell Biol., 74, 621-652, 2004. DOI: 10.1016/S0091-679X(04)74025-X
Dunn, A. R.; Dmochowski, I. J.; Winkler, J. R.; Gray, H. B., Nanosecond photoreduction of cytochrome P450cam by channel-specific Ru-diimine electron tunneling wires. J. Am. Chem. Soc., 125(41), 12450-12456, 2003. DOI: 10.1021/ja0294111
Dmochowski, I. J.; Dunn, A. R.; Wilker, J. J.; Crane, B. R.; Green, M. T.; Dawson, J. H.; Sligar, S. G.; Winkler, J. R.; Gray, H. B., Sensitizer-linked substrates and ligands: Ruthenium probes of cytochrome P450 structure and mechanism. Methods Enzymol., 357, 120-133, 2002. DOI: 10.1016/S0076-6879(02)57672-2
Dmochowski, I. J.; Dmochowski, J. E.; Oliveri, P.; Davidson, E. H.; Fraser, S. E., Quantitative imaging of cis-regulatory reporters in living embryos. Proc. Natl. Acad. Sci. U.S.A., 99(20), 12895-12900, 2002. DOI: 10.1073/pnas.202483199
Dunn, A. R.; Dmochowski, I. J.; Bilwes, A. M.; Gray, H. B.; Crane, B. R., Probing the open state of cytochrome P450cam with ruthenium-linker substrates. Proc. Natl. Acad. Sci. U.S.A., 98(22), 12420-12425, 2001. DOI: 10.1073/pnas.221297998
Bendix, J.; Dmochowski, I. J.; Gray, H. B.; Mahammed, A.; Simkhovich, L.; Gross, Z., Structural, Electrochemical, and Photophysical Properties of Gallium(III) 5,10,15?Tris(pentafluorophenyl)corrole. Angew. Chem. Int. Ed., 39(22), 4048-4051, 2000. DOI: 10.1002/1521-3773(20001117)39:22%3C4048::AID-ANIE4048%3E3.0.CO;2-7
Dmochowski, I. J.; Winkler, J. R.; Gray, H. B., Enantiomeric discrimination of Ru-substrates by cytochrome P450(cam). J. Inorg. Biochem., 81(3), 221-228, 2000. DOI: 10.1016/S0162-0134(00)00111-2
Dmochowski, I. J.; Crane, B. R.; Wilker, J. J.; Winkler, J. R.; Gray, H. B., Optical detection of cytochrome P450 by sensitizer-linked substrates. Proc. Natl. Acad. Sci. U.S.A., 96(23), 12987-12990. DOI: 10.1073/pnas.96.23.12987
Wilker, J. J.; Dmochowski, I. J.; Dawson, J. H.; Winkler, J. R.; Gray, H. B., Substrates for rapid delivery of electrons and holes to buried active sites in proteins. Angew. Chem. Int. Ed., 38(1-2), 89-92, 1999. DOI: 10.1002/(SICI)1521-3773(19990115)38:1/2<89::AID-ANIE89>3.0.CO;2-R
Wilker, J. J.; Dmochowski, I. J.; Dawson, J. H.; Winkler, J. R.; Gray, H. B., Production of high valent iron-oxo species in cytochrome P450-CAM by electron transfer through protein substrates. FASEB Journal, 11(9), 1997.
Rego, J. A.; Kumar, S.; Dmochowski, I. J.; Ringsdorf, H., Synthesis of novel mixed tail triphenylene discotic liquid crystals - The search for higher order. Chem. Commun., (9), 1031-1032, 1996. DOI: 10.1039/CC9960001031

Patents

I.J. Dmochowski, B.R. Crane, A.R. Dunn, H.B. Gray, J.J. Wilker, J.R. Winkler, Detection of biomolecules by sensitizer-linked substrates, serial number 10/031,532; patent number 7,105,310, issued 9/12/06.
I.J. Dmochowski, P.A. Hill, Q. Wei, N.N. Kuzma, 129Xe biosensors and their use, P-9049-USP, provisional filed 08/27/06, U.S. patent application filed 8/6/07.
I.J. Dmochowski, X. Tang, Photocleavable oligonucleotide and uses thereof, filed 12/04/06, provisional filed 11/27/07, U.S. patent application filed 11/08.
I.J. Dmochowski, P.A. Hill, Q. Wei, J.L. Chambers, Tri-functionalized cryptophanes and their use, provisional filed 07/07/08, U.S. patent application filed 7/07/09.
M. Jimbo, G. Robbins, N. Kamat, I.J. Dmochowski, M.J. Therien, D. Hammer, Polymer vesicles for selective electromagnetic energy-induced delivery, U.S. patent application #12/548,801 filed 8/27/09.