Publications
2024
- Z. Zhao, N.A. Rudman, J., I.J. Dmochowski. A Site-Specific Cross-Linker for Visible Light Control of Proteins. ACS Omega, 2024, 9, 27, 29331-29338.
2023
- J.T. Shieh, J.A.
Tintos-Hernandez, C.N. Murali, M. Penon-Portmann, M.
Flores-Mendez, A. Santana, J.A. Bulos, K. Du, L. Dupuis; N.
Damseh, et al. Heterozygous Nonsense Variants in the Ferritin
Heavy Chain Gene FTH1 Cause a Neuroferritinopathy. HGG advances,
2023. DOI: 10.1016/j.xhgg.2023/100236.
- K.
Du, P. Liao, S. Yang, D. von Trentini, K.
Sharma, X. Shi, C.B. Murray, D. Li, I.J.
Dmochowski. Chelate-functionalized magnetic
micelles for sequestration of cisplatin. Nanoscale
Adv., 2023. DOI: 10.1039/D3NA00290J.
- Z. Zhao, M. Zhou, S.D. Zemerov, R. Marmorstein, I.J. Dmochowski. Rational design of a genetically encoded NMR zinc sensor. Chem. Sci., 2023, 14, 3809-3815.
2022
- Z. Zhao, N.A. Rudman, J. He,
I.J. Dmochowski. Programming xenon diffusion in
maltose-binding protein. Biophys. J., 2022,
121(23), 4635-4643.
- Y. Lin, M.R. Gau, P.J. Carroll, I.J. Dmochowski. Counteranions at Peripheral Sites Tune Guest Affinity for a Protonated Hemicryptophane. J. Org. Chem., 2022, 87(8), 5158-5165.
2021
- J.A. Bulos, R. Guo, Z. Wang, M.A. DeLessio, J.G. Saven, I.J. Dmochowski. Design of a Superpositively Charged Enzyme: Human Carbonic Anhydrase II Variant with Ferritin Encapsulation and Immobilization. Biochemistry, 2021, 60(47). 3596-3609.
2020
- J.T. Shieh, A.J.
Tintos-Hernandez, A. Santana, J.A. Bulos, C. Berera,
J.J. Phillips, I.J. Dmochowski, X.R. Ortiz-Gonzalez.
FTH1De Novo Dominant Variants Alter Iron Metabolism and
Cause a Pediatric Onset Neuroferritinopathy. in Annals
of Neurology, 2020, 88, S216.
2019
2018
-
V.V. Shuvaev, M. Khoshnejad, K.W. Pulsipher, R.Y. Kiseleva, E. Arguiri, J.C. Cheung-Lau, K.M. LeFort, M. Christofidou-Solomidou, R.V. Stan, I.J. Dmochowski, V.R. Muzykantov, Spatially controlled assembly of affinity ligand and enzyme cargo enables targeting ferritinnanocarriers to caveolae, Biomaterials, 185, 348-359, 2018. DOI: 10.1016/j.biomaterials.2018.09.015
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B.W. Roose, S.D. Zemerov, I.J. Dmochowski. Xenon–Protein Interactions: Characterization by X-Ray Crystallography and Hyper-CEST NMR. In Methods in enzymology, 602, 249-272, 2018. Academic Press. DOI: 10.1016/bs.mie.2018.02.005
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B.W. Roose, S.D. Zemerov, Y. Wang, M. Kasimova, V. Carnevale, I.J. Dmochowski, A structural basis for Xe-129 Hyper-CEST signal in TEM-1 β-lactamase, ChemPhysChem, 19, 1-9, 2018. DOI: 10.1002/cphc.201800624. Cover feature. Highlighted in ChemistryViews.
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K.W. Pulsipher, J.A. Bulos, J.A. Villegas, J.G. Saven, I.J. Dmochowski, A protein-protein host-guest complex: Thermostable ferritin encapsulatingpositively supercharged green fluorescent protein, Prot. Sci., 27, 1755-1766, 2018. PMID: 30051936, DOI: 10.1002/pro.3483
- Zemerov, S.; Roose, B.; Greenberg, M.; Wang, Y.; Dmochowski, I. Cryptophane nanoscale assemblies expand Xe-129 NMR biosensing. Anal. Chem., 90(12), 7730-7738, 2018. PMCID: PMC6050516. DOI: 10.1021/acs.analchem.8b01630
- Khoshnejad, M.; Parhiz, H.; Shuvaev, V.; Dmochowski, I.; Muzykantov, V. Ferritin-based drug delivery systems: hybrid nanocarriers for vascular immunotargeting. J. Control. Release, 282, 13-24, 2018. PMCID: PMC6008199. DOI: 10.1016/j.jconrel.2018.02.042
- Yang, L.; Sul, J.-Y.; Kim, H.-B.; Yeldell, S.; Eberwine, J.; Dmochowski, I. Efficient synthesis of light-triggered circular antisense oligonucleotides targeting cellular protein expression. ChemBioChem, 19(12), 1250-1254, 2018. DOI: 10.1002/cbic.201800012
- Khoshnejad, M.;
Greineder, C.; Pulsipher, K.; Villa, C.; Altun, B.; Pan, D.;
Tsourkas, A.; Dmochowski, I.; Muzykantov, V. Ferritin
nanocarriers with biologically orthogonal conjugation for
vascular targeting and imaging. Bioconjug. Chem.,
29(4), 1209-1218, 2018. DOI: 10.1021/acs.bioconjchem.8b00004
- Zhang, L.; Liang, D.; Wang,
Y.; Gubu, A.; Yang, J.; Yu, L.; Dmochowski, I.; Tang, X. Circular
siRNAs for reducing off-target effects and enhancing long-term
gene silencing in cells and mice. Mol. Ther. Nucl.
Acids, 10, 237-244, 2018. PMCID: PMC5768153 DOI: 10.1016/j.omtn.2017.12.007
- T.L. Rapp, C.B. Highley,
B. Manor, J.A. Burdick, I.J. Dmochowski, Ruthenium-crosslinked
hydrogels with rapid, visible-light degradation, Chemistry-Eur.
J., 24 (10), 2328-2333, 2018. PMCID: PMC5915374
DOI: 10.1002/chem.201704580
2017
- Yeldell, S.; Ruble, B.;
Dmochowski, I. Oligonucleotide modifications enhance probe
stability for single cell transcriptome in vivo analysis
(TIVA). Org. Biomol. Chem., 15,
10001-10009, 2017. DOI: 10.1039/C7OB02353G
- Riggle, B. A.; Greenberg,
M.; Wang, Y.; Wissner, R. F.; Zemerov, S.; Petersson, J.;
Dmochowski, I. A cryptophane-based “turn-on” Xe-129 NMR
biosensor for monitoring calmodulin. Org. Biomol.
Chem., 15, 8883-8887, 2017. DOI: 10.1039/C7OB02391J
- Roose, B. W.; Zemerov, S.
D.; Dmochowski, I. J. Nanomolar small-molecule detection
using a genetically encoded Xe-129 NMR contrast agent. Chem.
Sci., 8, 7631-7636, 2017. DOI: 10.1039/C7SC03601A
- Pulsipher, K. W.; Honig,
S.; Deng, S.; Dmochowski, I. J. Controlling Gold
Nanoparticle Seeded Growth in Thermophilic Ferritin Protein
Templates. J. Inorg. Biochem., 174, 169-176, 2017.
DOI: 10.1016/j.jinorgbio.2017.06.012
- Pulsipher, K. W.;
Villegas, J. A.; Roose, B. W.; Hicks, T. L.; Yoon, J.; Saven, J.
G.; Dmochowski, I. J. Thermophilic Ferritin 24mer Assembly
and Nanoparticle Encapsulation Modulated by Interdimer
Electrostatic Repulsion. Biochemistry, 56(28),
3596-3606, 2017. DOI: 10.1021/acs.biochem.7b00296
- Ping, J.; Pulsipher, K.
W.; Vishnubhotla, R.; Villegas, J. A.; Hicks, T. L.; Honig, S.;
Saven, J. G.; Dmochowski, I. J.; Johnson, A. T. C. Structural-Functional
Analysis of Engineered Protein-Nanoparticle Assemblies Using
Graphene Microelectrodes. Chem. Sci., 8, 5329-5334,
2017. DOI: 10.1039/C7SC01565H
2016
- Wang, Y.; Dmochowski, I.
J. An Expanded Palette of Xenon-129 NMR Biosensors. Acc.
Chem. Res., 49(10), 2179-2187, 2016. DOI: 10.1021/acs.accounts.6b00309
- Pulsipher, K. W.;
Dmochowski, I. J. Ferritin: Versatile Host, Nanoreactor, and
Delivery Agent. Isr. J. Chem., 56,
660-670, 2016. DOI: 10.1002/ijch.201600017
- Wang, Y.; Roose, B. W.;
Palovcak, E. J.; Carnevale, V.; Dmochowski, I. J. A
Genetically Encoded ?-Lactamase Reporter for Ultrasensitive
Xe-129 NMR in Mammalian Cells. Angew. Chem. Int. Ed.,
55(31), 8984–8987, 2016. DOI: 10.1002/anie.201604055
- Khoshnejad, M.; Shuvaev,
V. V.; Pulsipher, K. W.; Dai, C.; Hood, E. D.; Arguiri, E.;
Christofidou-Solomidou, M.; Dmochowski, I. J.; Greineder, C. F.;
Muzykantov, V. R. Vascular Accessibility of Endothelial
Targeted Ferritin Nanoparticles. Bioconjug. Chem.,
27(3), 628-637, 2016. DOI: 10.1021/acs.bioconjchem.5b00641
- Y. Wang, B.W. Roose, J.P. Philbin, J.L. Doman, I.J. Dmochowski. Programming a molecular relay for ultrasensitive biodetection by 129Xe NMR. Angew. Chem. Int. Ed., 55(5), 1733-1736, 2016. DOI: 10.1002/anie.201508990
2015
- Gao, L.; Liu, W.; Lee, O.-S.; Dmochowski, I. J.; Saven, J. G. Xe affinities of water-soluble cryptophanes and the role of confined water. Chem. Sci., 6(12), 7238–7248, 2016. DOI: 10.1039/C5SC02401C
- Linganna, R. E.; Levy, W. J.; Dmochowski, I. J.; Eckenhoff, R. G.; Speck, R. M. Taxane modulation of anesthetic sensitivity in surgery for nonmetastatic breast cancer. J. Clin. Anesth., 27(6), 481–485, 2015. DOI: 10.1016/j.jclinane.2015.05.001
- Ruble,
B. K.; Yeldell, S. B.; Dmochowski, I. J. Caged
oligonucleotides for studying biological systems. J.
Inorg. Biochem., 150, 182-188, 2015. DOI: 10.1016/j.jinorgbio.2015.03.010
- Wang,
Y.; Dmochowski, I. J. Cucurbit[6]uril is an ultrasensitive
Xe-129 NMR contrast agent. Chem. Commun., 51(43),
8982–8985, 2015. DOI: 10.1039/C5CC01826A
- Riggle,
B. A.; Wang, Y.; Dmochowski, I. J. A “Smart” Xe-129 NMR
Biosensor for pH-Dependent Cell Labeling. J. Am. Chem.
Soc., 137(16), 5542-5548, 2015. DOI: 10.1021/jacs.5b01938
- Griepenburg,
J. C.; Sood, N.; Vargo, K. B.; Williams, D.; Rawson, J.;
Therien, M. J.; Hammer, D. A.; Dmochowski, I. J. Caging
Metal Ions with Visible Light-Responsive Nanopolymersomes.
Langmuir, 31(2), 799-807, 2015. DOI: 10.1021/la5036689
- Griepenburg,
J. C.; Rapp, T. L.; Carroll, P. J.; Eberwine, J.; Dmochowski, I.
J. Ruthenium-caged antisense morpholinos for regulating gene
expression in zebrafish embryos. Chem. Sci., 6,
2342–2346, 2015. DOI: 10.1039/C4SC03990D
- Taratula, O.; Bai, Y.; D’Antonio, E. L.; Dmochowski, I. J. Enantiopure cryptophane-129Xe nuclear magnetic resonance biosensors targeting carbonic anhydrase. Supramol. Chem., 27, 65-71, 2015. DOI: 10.108/10610278.2014.906601
2014
- Khan, N. S.; Riggle, B. A.; Seward, G. K.; Bai, Y.; Dmochowski, I. J. Cryptophane-Folate Biosensor for Xe-129 NMR. Bioconjug. Chem., 26(1), 101-109, 2014. DOI: 10.1021/bc5005526
- Bai, Y.; Wang, Y.; Goulian, M.; Driks, A.; Dmochowski, I. J. Bacterial spore detection and analysis using hyperpolarized 129Xe chemical exchange saturation transfer (Hyper-CEST) NMR. Chem. Sci., 5(8), 3197-3203, 2014. DOI: 10.1039/C4SC01190B
- Lovatt, D.; Ruble, B. K.; Lee, J.; Dueck, H.; Kim, T. K.; Fisher, S.; Francis, C.; Spaethling, J. M.; Wolf, J. a; Grady, M. S.; Ulyanova, A. V; Yeldell, S. B.; Griepenburg, J. C.; Buckley, P. T.; Kim, J.; Sul, J.-Y.; Dmochowski, I. J.; Eberwine, J. Transcriptome in vivo analysis (TIVA) of spatially defined single cells in live tissue. Nat. Methods, 11, 190-196, 2014. DOI: 10.1038/nmeth.2804
- Cheung-Lau, J. C.; Liu, D.; Pulsipher, K. W.; Liu, W.; Dmochowski, I. J. Engineering a well-ordered, functional protein-gold nanoparticle assembly. J. Inorg. Biochem., 130, 59-68, 2014. DOI: 10.1016/j.jinorgbio.2013.10.003
2013
- Liao, Z.; Hsieh, W.-T.; Baumgart, T.; Dmochowski, I.J.; Measuring interactions between polydimethylsiloxane and serum proteins at the air-water interface. Langmuir, 29(30), 9420-9427, 2013. DOI: 10.1021/la401619s
- Griepenburg, J. C.;
Ruble, B. K.; Dmochowski, I. J., Caged oligonucleotides for
bidirectional photomodulation of let-7 miRNA in zebrafish
embryos. Bioorg. Med. Chem., 21(20), 6198-6204.
DOI: 10.1016/j.bmc.2013.04.082
- Emerson, D. J.; Weiser,
B. P.; Psonis, J.; Liao, Z.; Taratula, O.; Fiamengo, A.; Wang,
X.; Sugasawa, K.; Smith Iii, A. B.; Eckenhoff, R. G.;
Dmochowski, I. J., Direct modulation of microtubule
stability contributes to anthracene general anesthesia. J. Am. Chem. Soc.,
135(14), 5289-5398, 2013.
DOI: 10.1021/ja311171u
2012
- Bai, Y.; Hill, P. A.;
Dmochowski, I. J., Utilizing a water-soluble cryptophane
with fast xenon exchange rates for picomolar sensitivity NMR
measurements. Anal. Chem., 84(22), 9935-9941,
2012. DOI: 10.1021/ac302347y
- Laureano-Perez, L.; Colle,
R.; Jacobson, D. R.; Fitzgerald, R.; Khan, N. S.; Dmochowski, I.
J., A novel application for Rn-222 emanation standards:
Radon-cryptophane host chemistry. Appl. Radiat. Isot.,
70(9), 1997-2001, 2012. DOI: 10.1016/j.apradiso.2012.02.099
- Taratula, O.; Kim, M. P.;
Bai, Y.; Philbin, J. P.; Riggle, B. A.; Haase, D. N.;
Dmochowski, I. J., Synthesis of enantiopure, trisubstituted
cryptophane-A derivatives. Org. Lett., 14(14),
3580-3583, 2012. DOI: 10.1021/ol300943w
- Emerson, D. J.; Liao, Z.;
Eckenhoff, R. G.; Dmochowski, I. J., A novel fluorescent
general anesthetic enables imaging of sites of action in vivo.
Anesthesiology, 116(6), 1363. DOI: 10.1097/ALN.0b013e31824cb4b1
- Bu, W.; Liu, R.;
Cheung-Lau, J. C.; Dmochowski, I. J.; Loll, P. J.; Eckenhoff, R.
G., Ferritin couples iron and fatty acid metabolism. FASEB
Journal, 26(6), 2394-2400, 2012. DOI: 10.1096/fj.11-198853
- Liu, R.; Bu, W.; Xi, J.;
Mortazavi, S. R.; Cheung-Lau, J. C.; Dmochowski, I. J.; Loll, P.
J., Beyond the detergent effect: A binding site for sodium
dodecyl sulfate (SDS) in mammalian apoferritin. Acta
Crystallographica Section D: Biological Crystallography,
68(5), 497-504, 2012. DOI: 10.1107/S0907444912002740
- Ruble, B. K.; Richards, J. L.; Cheung-Lau, J. C.; Dmochowski, I. J., Mismatch discrimination and efficient photomodulation with split 10-23 DNAzymes. Inorg. Chim. Acta, 380(1), 386-391, 2012. DOI: 10.1016/j.ica.2011.10.068
2011 and Before
- Liao, Z.; Lampe, J. W.;
Ayyaswamy, P. S.; Eckmann, D. M.; Dmochowski, I. J., Protein
assembly at the air-water interface studied by fluorescence
microscopy. Langmuir, 27(21), 12775-12781, 2011.
DOI: 10.1021/la203053g
- Kamat, N. P.; Liao, Z.;
Moses, L. E.; Rawson, J.; Therien, M. J.; Dmochowski, I. J.;
Hamme, D. A., Sensing membrane stress with near IR-emissive
porphyrins. Proc. Natl. Acad. Sci. U.S.A.,
108(34), 13984-13989, 2011. DOI: 10.1073/pnas.1102125108
- Jacobson, D. R.; Khan, N.
S.; Colle, R.; Fitzgerald, R.; Laureano-Perez, L.; Bai, Y.;
Dmochowski, I. J., Measurement of radon and xenon binding to
a cryptophane molecular host. Proc. Natl. Acad. Sci.
U.S.A.,
108(27), 10969-10973, 2011. DOI: 10.1073/pnas.1105227108
- Seward, G. K.; Bai, Y.;
Khan, N. S.; Dmochowski, I. J., Cell-compatible,
integrin-targeted cryptophane-Xe-129 NMR biosensors. Chem.
Sci., 2(6), 1103-1110, 2011. DOI: 10.1039/c1sc00041a
- Taratula, O.; Hill, P.
A.; Bai, Y.; Khan, N. S.; Dmochowski, I. J., Shorter
synthesis of trifunctionalized cryptophane - A derivatives.
Org. Lett., 13(6), 1414-1417, 2011. DOI: 10.1021/ol200088f
- Khan, N. S.;
Perez-Aguilar, J. M.; Kaufmann, T.; Hill, P. A.; Taratula, O.;
Lee, O. S.; Carroll, P. J.; Saven, J. G.; Dmochowski, I. J.,
Multiple hindered rotators in a gyroscope-inspired
tribenzylamine hemicryptophane. J. Org. Chem.,
76(5), 1418-1424, 2011. DOI: 10.1021/jo102480s
- Taratula, O.; Hill, P.
A.; Khan, N. S.; Carroll, P. J.; Dmochowski, I. J., Crystallographic
observation of 'induced fit' in a cryptophane host-guest model
system. Nat. Commun., 1, 2010. DOI: 10.1038/ncomms1151
- Kamat, N. P.; Robbins, G.
P.; Rawson, J.; Therien, M. J.; Dmochowski, I. J.; Hammer, D.
A., A generalized system for photoresponsive membrane
rupture in polymersomes. Adv. Funct. Mater.,
20(16), 2588-2596, 2010. DOI: 10.1002/adfm.201000659
- Lampe, J. W.; Liao, Z.;
Dmochowski, I. J.; Ayyaswamy, P. S.; Eckmann, D. M., Imaging
macromolecular interactions at an interface. Langmuir,
26(4), 2452-2459, 2010. DOI: 10.1021/la903703u
- Richards, J. L.; Seward,
G. K.; Wang, Y. H.; Dmochowski, I. J., Turning the 10-23
DNAzyme on and off with light. ChemBioChem, 11(3),
320-324, 2010. DOI: 10.1002/cbic.200900702
- Taratula, O.; Dmochowski,
I. J., Functionalized Xe-129 contrast agents for magnetic
resonance imaging. Curr. Opin. Chem. Biol., 14(1),
97-104, 2010. DOI: 10.1016/j.cbpa.2009.10.009
- Dmochowski, I., Xenon
out of its shell. Nat. Chem., 1(3), 250, 2009. DOI:
10.1038/nchem.230
- Swift, J.; Butts, C. A.;
Cheung-Lau, J.; Yerubandi, V.; Dmochowski, I. J., Efficient
Self-Assembly of Archaeoglobus fulgidus ferritin around
metallic cores. Langmuir, 25(9), 5219-5225, 2009.
DOI: 10.1021/la8040743
- Butts, C. A.; Xi, J.;
Brannigan, G.; Saad, A. A.; Venkatachalan, S. P.; Pearce, R. A.;
Klein, M. L.; Eckenhoff, R. G.; Dmochowski, I. J., Identification
of a fluorescent general anesthetic, 1-aminoanthracene. Proc.
Natl. Acad. Sci. U.S.A., 106(16),
6501-6506. DOI: 10.1073/pnas.0810590106
- Robbins, G. P.; Jimbo,
M.; Swift, J.; Therien, M. J.; Hammer, D. A.; Dmochowski, I. J.,
Photoinitiated destruction of composite Porphyrin-Protein
polymersomes. J. Am. Chem. Soc., 131(11),
3872-3874, 2009. DOI: 10.1021/ja808586q
- Aru Hill, P.; Wei, Q.;
Troxler, T.; Dmochowski, I. J., Substituent effects on xenon
binding affinity and solution behaviour of water-soluble
cryptophanes. J. Am. Chem. Soc., 131(8),
3069-3077, 2009. DOI: 10.1021/ja8100566
- Chambers, J. M.; Hill, P.
A.; Aaron, J. A.; Han, Z.; Christiansen, D. W.; Kuzma, N. N.;
Dmochowski, I. J., Cryptophane xenon-129 nuclear magnetic
resonance biosensors targeting human carbonic anhydrase. J.
Am. Chem. Soc., 131(2), 563-569. DOI: 10.1021/ja806092w
- Butts, C. A.; Swift, J.;
Kang, S. G.; Di Costanzo, L.; Christiansen, D. W.; Saven, J. G.;
Dmochowski, I. J., Directing noble metal ion chemistry
within a designed ferritin protein. Biochemistry,
47(48), 12729-12739, 2008. DOI: 10.1021/bi8016735
- Richards, J. L.; Tang,
X.; Turetsky, A.; Dmochowski, I. J., RNA bandages for
photoregulating in vitro protein synthesis. Bioorg.
Med. Chem. Lett., 18(23), 6255-6258. DOI: 10.1016/j.bmcl.2008.09.093
- Seward, G. K.; Wei, Q.;
Dmochowski, I. J., Peptide-mediated cellular uptake of
cryptophane. Bioconjug.
Chem., 19(11), 2129-2135, 2008.
DOI: 10.1021/bc8002265
- Aaron, J. A.; Chambers,
J. M.; Jude, K. M.; Di Costanzo, L.; Dmochowski, I. J.;
Christianson, D. W., Structure of a 129Xe-cryptophane
biosensor complexed with human carbonic anhydrase II. J. Am. Chem. Soc.,
130(22), 6942-6943, 2008.
DOI: 10.1021/ja802214x
- Tang, X.; Swaminathan,
J.; Gewirtz, A. M.; Dmochowski, I. J., Regulating gene
expression in human leukemia cells using light-activated
oligodeoxynucleotides. Nucleic Acids Res., 36(2),
559-569, 2008. DOI: 10.1093/nar/gkm1029
- Zhang, L.; Swift, J.;
Butts, C. A.; Yerubandi, V.; Dmochowski, I. J., Structure
and activity of apoferritin-stabilized gold nanoparticles.
J. Inorg. Biochem., 101(11-12), 1719-1729,
2007. DOI: 10.1016/j.jinorgbio.2007.07.023
- Hill, P. A.; Wei, Q.;
Eckenhoff, R. G.; Dmochowski, I. J., Erratum: Thermodynamics
of xenon binding to cryptophane in water and human plasma
(Journal of the American Chemical Society (2007) 129,
(9262-9263)).
J. Am. Chem. Soc., 129(37), 11662. DOI: 10.1021/ja075845q
- Tang, X.; Maegawa, S.;
Weinberg, E. S.; Dmochowski, I. J., Regulating gene
expression in zebrafish embryos using light-activated,
negatively charged peptide nucleic acids. J. Am. Chem. Soc.,
129(36), 11000-11001, 2007.
DOI: 10.1021/ja073723s
- Hill, P. A.; Wei, Q.;
Eckenhoff, R. G.; Dmochowski, I. J., Thermodynamics of xenon
binding to cryptophane in water and human plasma.
J.
Am. Chem. Soc.,
129(30),
9262-9263, 2007. DOI: 10.1021/ja072965p
- Dmochowski, I. J.; Tang,
X., Taking control of gene expression with light-activated
oligonucleotides. BioTechniques, 43(2), 161-171,
2007. DOI: 10.2144/000112519
- Dmochowski, I.; Tang, X.,
Probing expression. Org. Biomol. Chem., 5(3),
2007. DOI: 10.1039/C3OB41467A
- Tang, X.; Dmochowski, I.
J., Regulating gene expression with light-activated
oligonucleotides. Mol. BioSyst., 3(2), 100-110,
2007. DOI:
10.1039/b614349k
- Tang, X. J.; Dmochowski,
I. J., Synthesis of light-activated antisense
oligodeoxynucleotide. Nat. Protoc., 1(6),
3041-3048, 2007. DOI: 10.1038/nprot.2006.462
- Wei, Q.; Seward, G. K.;
Hill, P. A.; Patton, B.; Dimitrov, I. E.; Kuzma, N. N.;
Dmochowski, I. J., Designing Xe-129 NMR biosensors for
matrix metalloproteinase detection. J.
Am. Chem. Soc., 128(40), 13274-13283, 2006. DOI: 10.1021/ja0640501
- Swift, J.; Wehbi, W. A.;
Kelly, B. D.; Stowell, X. F.; Saven, J. G.; Dmochowski, I. J., Design
of functional ferritin-like proteins with hydrophobic cavities.
J. Am. Chem. Soc.,
128(20), 6611-6619, 2006. DOI:
10.1021/ja057069x
- Tang, X.; Dmochowski, I.
J., Controlling RNA digestion by RNase H with a
light-activated DNA hairpin. Angew.
Chem.
Int. Ed.,
45(21), 3523-3526, 2006. DOI: 10.1002/anie.200600954
- Agadjanian, H.; Weaver,
J. J.; Mahammed, A.; Rentsendorj, A.; Bass, S.; Kim, J.;
Dmochowski, I. J.; Margalit, R.; Gray, H. B.; Gross, Z.;
Medina-Kauwe, L. K., Specific delivery of corroles to cells
via noncovalent conjugates with viral proteins. Pharm.
Res., 23(2), 367-377, 2006. DOI: 10.1007/s11095-005-9225-1
- Tang, X.; Richards, J.
L.; Peritz, A. E.; Dmochowski, I. J., Photoregulation of DNA
polymerase I (Klenow) with caged fluorescent
oligodeoxynucleotides. Bioorg. Med. Chem. Lett.,
15(23), 5303-5306, 2005. DOI: 10.1016/j.bmcl.2005.08.058
- Tang, X.; Dmochowski, I.
J., Phototriggering of caged fluorescent
oligodeoxynucleotides. Org. Lett., 7(2), 279-282,
2005. DOI: 10.1021/ol047729n
- Arnone, M. I.;
Dmochowski, I. J.; Gache, C., Using reporter genes to study
cis-regulatory elements. Methods Cell Biol., 74,
621-652, 2004. DOI: 10.1016/S0091-679X(04)74025-X
- Dunn, A. R.; Dmochowski,
I. J.; Winkler, J. R.; Gray, H. B., Nanosecond
photoreduction of cytochrome P450cam by channel-specific
Ru-diimine electron tunneling wires. J. Am. Chem. Soc., 125(41), 12450-12456, 2003.
DOI: 10.1021/ja0294111
- Dmochowski, I. J.; Dunn,
A. R.; Wilker, J. J.; Crane, B. R.; Green, M. T.; Dawson, J. H.;
Sligar, S. G.; Winkler, J. R.; Gray, H. B., Sensitizer-linked
substrates and ligands: Ruthenium probes of cytochrome P450
structure and mechanism. Methods Enzymol., 357,
120-133, 2002. DOI: 10.1016/S0076-6879(02)57672-2
- Dmochowski, I. J.;
Dmochowski, J. E.; Oliveri, P.; Davidson, E. H.; Fraser, S. E.,
Quantitative imaging of cis-regulatory reporters in living
embryos. Proc.
Natl. Acad. Sci. U.S.A., 99(20), 12895-12900, 2002.
DOI:
10.1073/pnas.202483199
- Dunn, A. R.; Dmochowski,
I. J.; Bilwes, A. M.; Gray, H. B.; Crane, B. R., Probing the
open state of cytochrome P450cam with ruthenium-linker
substrates. Proc. Natl. Acad. Sci.
U.S.A.,
98(22), 12420-12425, 2001. DOI: 10.1073/pnas.221297998
- Bendix, J.; Dmochowski,
I. J.; Gray, H. B.; Mahammed, A.; Simkhovich, L.; Gross, Z., Structural,
Electrochemical, and Photophysical Properties of Gallium(III)
5,10,15?Tris(pentafluorophenyl)corrole. Angew.
Chem. Int. Ed., 39(22), 4048-4051, 2000.
DOI: 10.1002/1521-3773(20001117)39:22%3C4048::AID-ANIE4048%3E3.0.CO;2-7
- Dmochowski, I. J.;
Winkler, J. R.; Gray, H. B., Enantiomeric discrimination of
Ru-substrates by cytochrome P450(cam). J. Inorg.
Biochem., 81(3), 221-228, 2000. DOI: 10.1016/S0162-0134(00)00111-2
- Dmochowski, I. J.; Crane,
B. R.; Wilker, J. J.; Winkler, J. R.; Gray, H. B., Optical
detection of cytochrome P450 by sensitizer-linked substrates.
Proc. Natl. Acad. Sci.
U.S.A.,
96(23), 12987-12990. DOI: 10.1073/pnas.96.23.12987
- Wilker, J. J.;
Dmochowski, I. J.; Dawson, J. H.; Winkler, J. R.; Gray, H. B., Substrates
for rapid delivery of electrons and holes to buried active
sites in proteins. Angew.
Chem. Int. Ed.,
38(1-2), 89-92, 1999. DOI: 10.1002/(SICI)1521-3773(19990115)38:1/2<89::AID-ANIE89>3.0.CO;2-R
- Wilker, J. J.;
Dmochowski, I. J.; Dawson, J. H.; Winkler, J. R.; Gray, H. B.,
Production of high valent iron-oxo species in cytochrome
P450-CAM by electron transfer through protein substrates.
FASEB Journal, 11(9), 1997.
- Rego, J. A.; Kumar, S.; Dmochowski, I. J.; Ringsdorf, H., Synthesis of novel mixed tail triphenylene discotic liquid crystals - The search for higher order. Chem. Commun., (9), 1031-1032, 1996. DOI: 10.1039/CC9960001031
Patents
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I.J. Dmochowski, B.R. Crane, A.R. Dunn, H.B. Gray, J.J. Wilker, J.R. Winkler, Detection of biomolecules by sensitizer-linked substrates, serial number 10/031,532; patent number 7,105,310, issued 9/12/06.
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I.J. Dmochowski, P.A. Hill, Q. Wei, N.N. Kuzma, 129Xe biosensors and their use, P-9049-USP, provisional filed 08/27/06, U.S. patent application filed 8/6/07.
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I.J. Dmochowski, X. Tang, Photocleavable oligonucleotide and uses thereof, filed 12/04/06, provisional filed 11/27/07, U.S. patent application filed 11/08.
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I.J. Dmochowski, P.A. Hill, Q. Wei, J.L. Chambers, Tri-functionalized cryptophanes and their use, provisional filed 07/07/08, U.S. patent application filed 7/07/09.
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M. Jimbo, G. Robbins, N. Kamat, I.J. Dmochowski, M.J. Therien, D. Hammer, Polymer vesicles for selective electromagnetic energy-induced delivery, U.S. patent application #12/548,801 filed 8/27/09.