Dmochowski Group

Publications


2024

Figure 1

2023

  2022


  2021

  2020

  • J.T. Shieh, A.J. Tintos-Hernandez, A. Santana, J.A. Bulos, C. Berera, J.J. Phillips, I.J. Dmochowski, X.R. Ortiz-Gonzalez. FTH1De Novo Dominant Variants Alter Iron Metabolism and Cause a Pediatric Onset Neuroferritinopathy. in Annals of Neurology, 2020, 88, S216.

  2019



2018

  • V.V. Shuvaev, M. Khoshnejad, K.W. Pulsipher, R.Y. Kiseleva, E. Arguiri, J.C. Cheung-Lau, K.M. LeFort, M. Christofidou-Solomidou, R.V. Stan, I.J. Dmochowski, V.R. Muzykantov, Spatially controlled assembly of affinity ligand and enzyme cargo enables targeting ferritinnanocarriers to caveolae, Biomaterials, 185, 348-359, 2018. DOI: 10.1016/j.biomaterials.2018.09.015
  • B.W. Roose, S.D. Zemerov, I.J. Dmochowski. Xenon–Protein Interactions: Characterization by X-Ray Crystallography and Hyper-CEST NMR. In Methods in enzymology, 602, 249-272, 2018. Academic Press. DOI: 10.1016/bs.mie.2018.02.005
  • B.W. Roose, S.D. Zemerov, Y. Wang, M. Kasimova, V. Carnevale, I.J. Dmochowski, A structural basis for Xe-129 Hyper-CEST signal in TEM-1 β-lactamase, ChemPhysChem, 19, 1-9, 2018. DOI: 10.1002/cphc.201800624. Cover feature. Highlighted in ChemistryViews.
  • K.W. Pulsipher, J.A. Bulos, J.A. Villegas, J.G. Saven, I.J. Dmochowski, A protein-protein host-guest complex: Thermostable ferritin encapsulatingpositively supercharged green fluorescent protein, Prot. Sci., 27, 1755-1766, 2018. PMID: 30051936, DOI: 10.1002/pro.3483
  • Zemerov, S.; Roose, B.; Greenberg, M.; Wang, Y.; Dmochowski, I. Cryptophane nanoscale assemblies expand Xe-129 NMR biosensing. Anal. Chem., 90(12), 7730-7738, 2018. PMCID: PMC6050516. DOI: 10.1021/acs.analchem.8b01630
TOC figure
  • Khoshnejad, M.; Parhiz, H.; Shuvaev, V.; Dmochowski, I.; Muzykantov, V. Ferritin-based drug delivery systems: hybrid nanocarriers for vascular immunotargeting. J. Control. Release, 282, 13-24, 2018. PMCID: PMC6008199. DOI: 10.1016/j.jconrel.2018.02.042
TOC figure
  • Yang, L.; Sul, J.-Y.; Kim, H.-B.; Yeldell, S.; Eberwine, J.; Dmochowski, I. Efficient synthesis of light-triggered circular antisense oligonucleotides targeting cellular protein expression. ChemBioChem, 19(12), 1250-1254, 2018. DOI: 10.1002/cbic.201800012
TOC figure

  • Khoshnejad, M.; Greineder, C.; Pulsipher, K.; Villa, C.; Altun, B.; Pan, D.; Tsourkas, A.; Dmochowski, I.; Muzykantov, V. Ferritin nanocarriers with biologically orthogonal conjugation for vascular targeting and imaging. Bioconjug. Chem., 29(4), 1209-1218, 2018. DOI: 10.1021/acs.bioconjchem.8b00004
TOC Figure
  • Zhang, L.; Liang, D.; Wang, Y.; Gubu, A.; Yang, J.; Yu, L.; Dmochowski, I.; Tang, X. Circular siRNAs for reducing off-target effects and enhancing long-term gene silencing in cells and mice. Mol. Ther. Nucl. Acids, 10, 237-244, 2018. PMCID: PMC5768153 DOI: 10.1016/j.omtn.2017.12.007
Graphical abstract
  • T.L. Rapp, C.B. Highley, B. Manor, J.A. Burdick, I.J. Dmochowski, Ruthenium-crosslinked hydrogels with rapid, visible-light degradation, Chemistry-Eur. J., 24 (10), 2328-2333, 2018. PMCID: PMC5915374 DOI: 10.1002/chem.201704580
Graphical abstract



  2017

  • Yeldell, S.; Ruble, B.; Dmochowski, I. Oligonucleotide modifications enhance probe stability for single cell transcriptome in vivo analysis (TIVA). Org. Biomol. Chem., 15, 10001-10009, 2017. DOI: 10.1039/C7OB02353G
Yeldell et al 2017
  • Riggle, B. A.; Greenberg, M.; Wang, Y.; Wissner, R. F.; Zemerov, S.; Petersson, J.; Dmochowski, I. A cryptophane-based “turn-on” Xe-129 NMR biosensor for monitoring calmodulin. Org. Biomol. Chem., 15, 8883-8887, 2017. DOI: 10.1039/C7OB02391J
Riggle et al 2017
  • Roose, B. W.; Zemerov, S. D.; Dmochowski, I. J. Nanomolar small-molecule detection using a genetically encoded Xe-129 NMR contrast agent. Chem. Sci., 8, 7631-7636, 2017. DOI: 10.1039/C7SC03601A
Roose et al 2017
  • Pulsipher, K. W.; Honig, S.; Deng, S.; Dmochowski, I. J. Controlling Gold Nanoparticle Seeded Growth in Thermophilic Ferritin Protein Templates. J. Inorg. Biochem., 174, 169-176, 2017. DOI: 10.1016/j.jinorgbio.2017.06.012
Pulsipher_InorgBiochem_2017
  • Pulsipher, K. W.; Villegas, J. A.; Roose, B. W.; Hicks, T. L.; Yoon, J.; Saven, J. G.; Dmochowski, I. J. Thermophilic Ferritin 24mer Assembly and Nanoparticle Encapsulation Modulated by Interdimer Electrostatic Repulsion. Biochemistry, 56(28), 3596-3606, 2017. DOI: 10.1021/acs.biochem.7b00296
Pulsipher_Biochemistry_2017
  • Ping, J.; Pulsipher, K. W.; Vishnubhotla, R.; Villegas, J. A.; Hicks, T. L.; Honig, S.; Saven, J. G.; Dmochowski, I. J.; Johnson, A. T. C. Structural-Functional Analysis of Engineered Protein-Nanoparticle Assemblies Using Graphene Microelectrodes. Chem. Sci., 8, 5329-5334, 2017. DOI: 10.1039/C7SC01565H
Ping_ChemSci_2017


  2016

  • Wang, Y.; Dmochowski, I. J. An Expanded Palette of Xenon-129 NMR Biosensors. Acc. Chem. Res., 49(10), 2179-2187, 2016. DOI: 10.1021/acs.accounts.6b00309

Wang_AccChemRes_2016
  • Pulsipher, K. W.; Dmochowski, I. J. Ferritin: Versatile Host, Nanoreactor, and Delivery AgentIsr. J. Chem., 56, 660-670, 2016. DOI: 10.1002/ijch.201600017
Abstract image
  • Wang, Y.; Roose, B. W.; Palovcak, E. J.; Carnevale, V.; Dmochowski, I. J. A Genetically Encoded ?-Lactamase Reporter for Ultrasensitive Xe-129 NMR in Mammalian Cells. Angew. Chem. Int. Ed., 55(31), 8984–8987, 2016. DOI: 10.1002/anie.201604055

Abstract image
  • Khoshnejad, M.; Shuvaev, V. V.; Pulsipher, K. W.; Dai, C.; Hood, E. D.; Arguiri, E.; Christofidou-Solomidou, M.; Dmochowski, I. J.; Greineder, C. F.; Muzykantov, V. R. Vascular Accessibility of Endothelial Targeted Ferritin Nanoparticles. Bioconjug. Chem., 27(3), 628-637, 2016. DOI: 10.1021/acs.bioconjchem.5b00641
Abstract_image
  • Y. Wang, B.W. Roose, J.P. Philbin, J.L. Doman, I.J. Dmochowski. Programming a molecular relay for ultrasensitive biodetection by 129Xe NMR. Angew. Chem. Int. Ed., 55(5), 1733-1736, 2016. DOI: 10.1002/anie.201508990
Wang_Angew_2015

  2015

  • Gao, L.; Liu, W.; Lee, O.-S.; Dmochowski, I. J.; Saven, J. G. Xe affinities of water-soluble cryptophanes and the role of confined water. Chem. Sci., 6(12), 7238–7248, 2016. DOI: 10.1039/C5SC02401C
  • Linganna, R. E.; Levy, W. J.; Dmochowski, I. J.; Eckenhoff, R. G.; Speck, R. M. Taxane modulation of anesthetic sensitivity in surgery for nonmetastatic breast cancer. J. Clin. Anesth., 27(6), 481–485, 2015. DOI: 10.1016/j.jclinane.2015.05.001
  • Ruble, B. K.; Yeldell, S. B.; Dmochowski, I. J. Caged oligonucleotides for studying biological systems. J. Inorg. Biochem., 150, 182-188, 2015. DOI: 10.1016/j.jinorgbio.2015.03.010
Oligo
  • Wang, Y.; Dmochowski, I. J. Cucurbit[6]uril is an ultrasensitive Xe-129 NMR contrast agent. Chem. Commun., 51(43), 8982–8985, 2015. DOI: 10.1039/C5CC01826A
Wang_ChemComm_2015
  • Riggle, B. A.; Wang, Y.; Dmochowski, I. J. A “Smart” Xe-129 NMR Biosensor for pH-Dependent Cell Labeling. J. Am. Chem. Soc., 137(16), 5542-5548, 2015. DOI: 10.1021/jacs.5b01938

Smart Xe biosensor
  • Griepenburg, J. C.; Sood, N.; Vargo, K. B.; Williams, D.; Rawson, J.; Therien, M. J.; Hammer, D. A.; Dmochowski, I. J. Caging Metal Ions with Visible Light-Responsive Nanopolymersomes. Langmuir, 31(2), 799-807, 2015. DOI: 10.1021/la5036689
Griepenburg_Langmuir_2015
  • Griepenburg, J. C.; Rapp, T. L.; Carroll, P. J.; Eberwine, J.; Dmochowski, I. J. Ruthenium-caged antisense morpholinos for regulating gene expression in zebrafish embryos. Chem. Sci., 6, 2342–2346, 2015. DOI: 10.1039/C4SC03990D
Griepenburg_ChemSci_2014

  • Taratula, O.; Bai, Y.; D’Antonio, E. L.; Dmochowski, I. J. Enantiopure cryptophane-129Xe nuclear magnetic resonance biosensors targeting carbonic anhydrase. Supramol. Chem., 27, 65-71, 2015. DOI: 10.108/10610278.2014.906601
Supramolecular Chemistry_2014


  2014

  • Khan, N. S.; Riggle, B. A.; Seward, G. K.; Bai, Y.; Dmochowski, I. J. Cryptophane-Folate Biosensor for Xe-129 NMR. Bioconjug. Chem., 26(1), 101-109, 2014. DOI: 10.1021/bc5005526
graphical abstract
  • Bai, Y.; Wang, Y.; Goulian, M.; Driks, A.; Dmochowski, I. J. Bacterial spore detection and analysis using hyperpolarized 129Xe chemical exchange saturation transfer (Hyper-CEST) NMR. Chem. Sci., 5(8), 3197-3203, 2014. DOI: 10.1039/C4SC01190B
Spores
  • Lovatt, D.; Ruble, B. K.; Lee, J.; Dueck, H.; Kim, T. K.; Fisher, S.; Francis, C.; Spaethling, J. M.; Wolf, J. a; Grady, M. S.; Ulyanova, A. V; Yeldell, S. B.; Griepenburg, J. C.; Buckley, P. T.; Kim, J.; Sul, J.-Y.; Dmochowski, I. J.; Eberwine, J. Transcriptome in vivo analysis (TIVA) of spatially defined single cells in live tissue. Nat. Methods, 11, 190-196, 2014. DOI: 10.1038/nmeth.2804
Lovatt et al., 2014_graphical abstract
  • Cheung-Lau, J. C.; Liu, D.; Pulsipher, K. W.; Liu, W.; Dmochowski, I. J. Engineering a well-ordered, functional protein-gold nanoparticle assembly. J. Inorg. Biochem., 130, 59-68, 2014. DOI: 10.1016/j.jinorgbio.2013.10.003
abstract_image_10


  2013

  • Liao, Z.; Hsieh, W.-T.; Baumgart, T.; Dmochowski, I.J.; Measuring interactions between polydimethylsiloxane and serum proteins at the air-water interface. Langmuir, 29(30), 9420-9427, 2013. DOI: 10.1021/la401619s
abstract_image_09
  • Griepenburg, J. C.; Ruble, B. K.; Dmochowski, I. J., Caged oligonucleotides for bidirectional photomodulation of let-7 miRNA in zebrafish embryos. Bioorg. Med. Chem., 21(20), 6198-6204. DOI: 10.1016/j.bmc.2013.04.082
abstract_image_01
  • Emerson, D. J.; Weiser, B. P.; Psonis, J.; Liao, Z.; Taratula, O.; Fiamengo, A.; Wang, X.; Sugasawa, K.; Smith Iii, A. B.; Eckenhoff, R. G.; Dmochowski, I. J., Direct modulation of microtubule stability contributes to anthracene general anesthesia. J. Am. Chem. Soc., 135(14), 5289-5398, 2013. DOI: 10.1021/ja311171u
abstract_image_02


  2012

  • Bai, Y.; Hill, P. A.; Dmochowski, I. J., Utilizing a water-soluble cryptophane with fast xenon exchange rates for picomolar sensitivity NMR measurements. Anal. Chem., 84(22), 9935-9941, 2012. DOI: 10.1021/ac302347y
abstract_image_03
  • Laureano-Perez, L.; Colle, R.; Jacobson, D. R.; Fitzgerald, R.; Khan, N. S.; Dmochowski, I. J., A novel application for Rn-222 emanation standards: Radon-cryptophane host chemistry. Appl. Radiat. Isot., 70(9), 1997-2001, 2012. DOI: 10.1016/j.apradiso.2012.02.099
abstract_image_04
  • Taratula, O.; Kim, M. P.; Bai, Y.; Philbin, J. P.; Riggle, B. A.; Haase, D. N.; Dmochowski, I. J., Synthesis of enantiopure, trisubstituted cryptophane-A derivatives. Org. Lett., 14(14), 3580-3583, 2012. DOI: 10.1021/ol300943w
abstract_image_05
  • Emerson, D. J.; Liao, Z.; Eckenhoff, R. G.; Dmochowski, I. J., A novel fluorescent general anesthetic enables imaging of sites of action in vivo. Anesthesiology, 116(6), 1363. DOI: 10.1097/ALN.0b013e31824cb4b1
abstract_image_06
  • Bu, W.; Liu, R.; Cheung-Lau, J. C.; Dmochowski, I. J.; Loll, P. J.; Eckenhoff, R. G., Ferritin couples iron and fatty acid metabolism. FASEB Journal, 26(6), 2394-2400, 2012. DOI: 10.1096/fj.11-198853
abstract_image_07
  • Liu, R.; Bu, W.; Xi, J.; Mortazavi, S. R.; Cheung-Lau, J. C.; Dmochowski, I. J.; Loll, P. J., Beyond the detergent effect: A binding site for sodium dodecyl sulfate (SDS) in mammalian apoferritin. Acta Crystallographica Section D: Biological Crystallography, 68(5), 497-504, 2012. DOI: 10.1107/S0907444912002740
abstract_image_08
  • Ruble, B. K.; Richards, J. L.; Cheung-Lau, J. C.; Dmochowski, I. J., Mismatch discrimination and efficient photomodulation with split 10-23 DNAzymes. Inorg. Chim. Acta, 380(1), 386-391, 2012. DOI: 10.1016/j.ica.2011.10.068


  2011 and Before

  • Liao, Z.; Lampe, J. W.; Ayyaswamy, P. S.; Eckmann, D. M.; Dmochowski, I. J., Protein assembly at the air-water interface studied by fluorescence microscopy. Langmuir, 27(21), 12775-12781, 2011. DOI: 10.1021/la203053g
  • Kamat, N. P.; Liao, Z.; Moses, L. E.; Rawson, J.; Therien, M. J.; Dmochowski, I. J.; Hamme, D. A., Sensing membrane stress with near IR-emissive porphyrins. Proc. Natl. Acad. Sci. U.S.A., 108(34), 13984-13989, 2011. DOI: 10.1073/pnas.1102125108
  • Jacobson, D. R.; Khan, N. S.; Colle, R.; Fitzgerald, R.; Laureano-Perez, L.; Bai, Y.; Dmochowski, I. J., Measurement of radon and xenon binding to a cryptophane molecular hostProc. Natl. Acad. Sci. U.S.A., 108(27), 10969-10973, 2011. DOI: 10.1073/pnas.1105227108
  • Seward, G. K.; Bai, Y.; Khan, N. S.; Dmochowski, I. J., Cell-compatible, integrin-targeted cryptophane-Xe-129 NMR biosensors. Chem. Sci., 2(6), 1103-1110, 2011. DOI: 10.1039/c1sc00041a
  • Taratula, O.; Hill, P. A.; Bai, Y.; Khan, N. S.; Dmochowski, I. J., Shorter synthesis of trifunctionalized cryptophane - A derivatives. Org. Lett., 13(6), 1414-1417, 2011. DOI: 10.1021/ol200088f
  • Khan, N. S.; Perez-Aguilar, J. M.; Kaufmann, T.; Hill, P. A.; Taratula, O.; Lee, O. S.; Carroll, P. J.; Saven, J. G.; Dmochowski, I. J., Multiple hindered rotators in a gyroscope-inspired tribenzylamine hemicryptophane. J. Org. Chem., 76(5), 1418-1424, 2011. DOI: 10.1021/jo102480s
  • Taratula, O.; Hill, P. A.; Khan, N. S.; Carroll, P. J.; Dmochowski, I. J., Crystallographic observation of 'induced fit' in a cryptophane host-guest model system. Nat. Commun., 1, 2010. DOI: 10.1038/ncomms1151
  • Kamat, N. P.; Robbins, G. P.; Rawson, J.; Therien, M. J.; Dmochowski, I. J.; Hammer, D. A., A generalized system for photoresponsive membrane rupture in polymersomes. Adv. Funct. Mater., 20(16), 2588-2596, 2010. DOI: 10.1002/adfm.201000659
  • Lampe, J. W.; Liao, Z.; Dmochowski, I. J.; Ayyaswamy, P. S.; Eckmann, D. M., Imaging macromolecular interactions at an interface. Langmuir, 26(4), 2452-2459, 2010. DOI: 10.1021/la903703u
  • Richards, J. L.; Seward, G. K.; Wang, Y. H.; Dmochowski, I. J., Turning the 10-23 DNAzyme on and off with light. ChemBioChem, 11(3), 320-324, 2010. DOI: 10.1002/cbic.200900702
  • Taratula, O.; Dmochowski, I. J., Functionalized Xe-129 contrast agents for magnetic resonance imaging. Curr. Opin. Chem. Biol., 14(1), 97-104, 2010. DOI: 10.1016/j.cbpa.2009.10.009
  • Dmochowski, I., Xenon out of its shell. Nat. Chem., 1(3), 250, 2009. DOI: 10.1038/nchem.230
  • Swift, J.; Butts, C. A.; Cheung-Lau, J.; Yerubandi, V.; Dmochowski, I. J., Efficient Self-Assembly of Archaeoglobus fulgidus ferritin around metallic cores. Langmuir, 25(9), 5219-5225, 2009. DOI: 10.1021/la8040743
  • Butts, C. A.; Xi, J.; Brannigan, G.; Saad, A. A.; Venkatachalan, S. P.; Pearce, R. A.; Klein, M. L.; Eckenhoff, R. G.; Dmochowski, I. J., Identification of a fluorescent general anesthetic, 1-aminoanthraceneProc. Natl. Acad. Sci. U.S.A., 106(16), 6501-6506. DOI: 10.1073/pnas.0810590106
  • Robbins, G. P.; Jimbo, M.; Swift, J.; Therien, M. J.; Hammer, D. A.; Dmochowski, I. J., Photoinitiated destruction of composite Porphyrin-Protein polymersomes. J. Am. Chem. Soc., 131(11), 3872-3874, 2009. DOI: 10.1021/ja808586q
  • Aru Hill, P.; Wei, Q.; Troxler, T.; Dmochowski, I. J., Substituent effects on xenon binding affinity and solution behaviour of water-soluble cryptophanes. J. Am. Chem. Soc., 131(8), 3069-3077, 2009. DOI: 10.1021/ja8100566
  • Chambers, J. M.; Hill, P. A.; Aaron, J. A.; Han, Z.; Christiansen, D. W.; Kuzma, N. N.; Dmochowski, I. J., Cryptophane xenon-129 nuclear magnetic resonance biosensors targeting human carbonic anhydrase. J. Am. Chem. Soc., 131(2), 563-569. DOI: 10.1021/ja806092w
  • Butts, C. A.; Swift, J.; Kang, S. G.; Di Costanzo, L.; Christiansen, D. W.; Saven, J. G.; Dmochowski, I. J., Directing noble metal ion chemistry within a designed ferritin protein. Biochemistry, 47(48), 12729-12739, 2008. DOI: 10.1021/bi8016735
  • Richards, J. L.; Tang, X.; Turetsky, A.; Dmochowski, I. J., RNA bandages for photoregulating in vitro protein synthesis. Bioorg. Med. Chem. Lett., 18(23), 6255-6258. DOI: 10.1016/j.bmcl.2008.09.093
  • Seward, G. K.; Wei, Q.; Dmochowski, I. J., Peptide-mediated cellular uptake of cryptophane. Bioconjug. Chem., 19(11), 2129-2135, 2008. DOI: 10.1021/bc8002265
  • Aaron, J. A.; Chambers, J. M.; Jude, K. M.; Di Costanzo, L.; Dmochowski, I. J.; Christianson, D. W., Structure of a 129Xe-cryptophane biosensor complexed with human carbonic anhydrase II. J. Am. Chem. Soc., 130(22), 6942-6943, 2008. DOI: 10.1021/ja802214x
  • Tang, X.; Swaminathan, J.; Gewirtz, A. M.; Dmochowski, I. J., Regulating gene expression in human leukemia cells using light-activated oligodeoxynucleotides. Nucleic Acids Res., 36(2), 559-569, 2008. DOI: 10.1093/nar/gkm1029
  • Zhang, L.; Swift, J.; Butts, C. A.; Yerubandi, V.; Dmochowski, I. J., Structure and activity of apoferritin-stabilized gold nanoparticles. J. Inorg. Biochem., 101(11-12), 1719-1729, 2007. DOI: 10.1016/j.jinorgbio.2007.07.023
  • Hill, P. A.; Wei, Q.; Eckenhoff, R. G.; Dmochowski, I. J., Erratum: Thermodynamics of xenon binding to cryptophane in water and human plasma (Journal of the American Chemical Society (2007) 129, (9262-9263)). J. Am. Chem. Soc., 129(37), 11662. DOI: 10.1021/ja075845q
  • Tang, X.; Maegawa, S.; Weinberg, E. S.; Dmochowski, I. J., Regulating gene expression in zebrafish embryos using light-activated, negatively charged peptide nucleic acids. J. Am. Chem. Soc., 129(36), 11000-11001, 2007. DOI: 10.1021/ja073723s
  • Hill, P. A.; Wei, Q.; Eckenhoff, R. G.; Dmochowski, I. J., Thermodynamics of xenon binding to cryptophane in water and human plasma. J. Am. Chem. Soc., 129(30), 9262-9263, 2007. DOI: 10.1021/ja072965p
  • Dmochowski, I. J.; Tang, X., Taking control of gene expression with light-activated oligonucleotides. BioTechniques, 43(2), 161-171, 2007. DOI: 10.2144/000112519
  • Dmochowski, I.; Tang, X., Probing expression. Org. Biomol. Chem., 5(3), 2007. DOI: 10.1039/C3OB41467A
  • Tang, X.; Dmochowski, I. J., Regulating gene expression with light-activated oligonucleotides. Mol. BioSyst., 3(2), 100-110, 2007. DOI: 10.1039/b614349k
  • Tang, X. J.; Dmochowski, I. J., Synthesis of light-activated antisense oligodeoxynucleotide. Nat. Protoc., 1(6), 3041-3048, 2007. DOI: 10.1038/nprot.2006.462
  • Wei, Q.; Seward, G. K.; Hill, P. A.; Patton, B.; Dimitrov, I. E.; Kuzma, N. N.; Dmochowski, I. J., Designing Xe-129 NMR biosensors for matrix metalloproteinase detection. J. Am. Chem. Soc., 128(40), 13274-13283, 2006. DOI: 10.1021/ja0640501
  • Swift, J.; Wehbi, W. A.; Kelly, B. D.; Stowell, X. F.; Saven, J. G.; Dmochowski, I. J., Design of functional ferritin-like proteins with hydrophobic cavities. J. Am. Chem. Soc., 128(20), 6611-6619, 2006. DOI: 10.1021/ja057069x
  • Tang, X.; Dmochowski, I. J., Controlling RNA digestion by RNase H with a light-activated DNA hairpin Angew. Chem. Int. Ed., 45(21), 3523-3526, 2006. DOI: 10.1002/anie.200600954
  • Agadjanian, H.; Weaver, J. J.; Mahammed, A.; Rentsendorj, A.; Bass, S.; Kim, J.; Dmochowski, I. J.; Margalit, R.; Gray, H. B.; Gross, Z.; Medina-Kauwe, L. K., Specific delivery of corroles to cells via noncovalent conjugates with viral proteins. Pharm. Res., 23(2), 367-377, 2006. DOI: 10.1007/s11095-005-9225-1
  • Tang, X.; Richards, J. L.; Peritz, A. E.; Dmochowski, I. J., Photoregulation of DNA polymerase I (Klenow) with caged fluorescent oligodeoxynucleotides. Bioorg. Med. Chem. Lett., 15(23), 5303-5306, 2005. DOI: 10.1016/j.bmcl.2005.08.058
  • Tang, X.; Dmochowski, I. J., Phototriggering of caged fluorescent oligodeoxynucleotides. Org. Lett., 7(2), 279-282, 2005. DOI: 10.1021/ol047729n
  • Arnone, M. I.; Dmochowski, I. J.; Gache, C., Using reporter genes to study cis-regulatory elements. Methods Cell Biol., 74, 621-652, 2004. DOI: 10.1016/S0091-679X(04)74025-X
  • Dunn, A. R.; Dmochowski, I. J.; Winkler, J. R.; Gray, H. B., Nanosecond photoreduction of cytochrome P450cam by channel-specific Ru-diimine electron tunneling wiresJ. Am. Chem. Soc., 125(41), 12450-12456, 2003. DOI: 10.1021/ja0294111
  • Dmochowski, I. J.; Dunn, A. R.; Wilker, J. J.; Crane, B. R.; Green, M. T.; Dawson, J. H.; Sligar, S. G.; Winkler, J. R.; Gray, H. B., Sensitizer-linked substrates and ligands: Ruthenium probes of cytochrome P450 structure and mechanism. Methods Enzymol., 357, 120-133, 2002. DOI: 10.1016/S0076-6879(02)57672-2
  • Dmochowski, I. J.; Dmochowski, J. E.; Oliveri, P.; Davidson, E. H.; Fraser, S. E., Quantitative imaging of cis-regulatory reporters in living embryos. Proc. Natl. Acad. Sci. U.S.A., 99(20), 12895-12900, 2002. DOI: 10.1073/pnas.202483199
  • Dunn, A. R.; Dmochowski, I. J.; Bilwes, A. M.; Gray, H. B.; Crane, B. R., Probing the open state of cytochrome P450cam with ruthenium-linker substratesProc. Natl. Acad. Sci. U.S.A., 98(22), 12420-12425, 2001. DOI: 10.1073/pnas.221297998
  • Bendix, J.; Dmochowski, I. J.; Gray, H. B.; Mahammed, A.; Simkhovich, L.; Gross, Z., Structural, Electrochemical, and Photophysical Properties of Gallium(III) 5,10,15?Tris(pentafluorophenyl)corrole. Angew. Chem. Int. Ed., 39(22), 4048-4051, 2000. DOI: 10.1002/1521-3773(20001117)39:22%3C4048::AID-ANIE4048%3E3.0.CO;2-7
  • Dmochowski, I. J.; Winkler, J. R.; Gray, H. B., Enantiomeric discrimination of Ru-substrates by cytochrome P450(cam). J. Inorg. Biochem., 81(3), 221-228, 2000. DOI: 10.1016/S0162-0134(00)00111-2
  • Dmochowski, I. J.; Crane, B. R.; Wilker, J. J.; Winkler, J. R.; Gray, H. B., Optical detection of cytochrome P450 by sensitizer-linked substrates. Proc. Natl. Acad. Sci. U.S.A., 96(23), 12987-12990. DOI: 10.1073/pnas.96.23.12987
  • Wilker, J. J.; Dmochowski, I. J.; Dawson, J. H.; Winkler, J. R.; Gray, H. B., Substrates for rapid delivery of electrons and holes to buried active sites in proteins. Angew. Chem. Int. Ed., 38(1-2), 89-92, 1999. DOI: 10.1002/(SICI)1521-3773(19990115)38:1/2<89::AID-ANIE89>3.0.CO;2-R
  • Wilker, J. J.; Dmochowski, I. J.; Dawson, J. H.; Winkler, J. R.; Gray, H. B., Production of high valent iron-oxo species in cytochrome P450-CAM by electron transfer through protein substrates. FASEB Journal, 11(9), 1997.
  • Rego, J. A.; Kumar, S.; Dmochowski, I. J.; Ringsdorf, H., Synthesis of novel mixed tail triphenylene discotic liquid crystals - The search for higher order. Chem. Commun., (9), 1031-1032, 1996. DOI: 10.1039/CC9960001031

Patents

  • I.J. Dmochowski, B.R. Crane, A.R. Dunn, H.B. Gray, J.J. Wilker, J.R. Winkler, Detection of biomolecules by sensitizer-linked substrates, serial number 10/031,532; patent number 7,105,310, issued 9/12/06.

  • I.J. Dmochowski, P.A. Hill, Q. Wei, N.N. Kuzma, 129Xe biosensors and their use, P-9049-USP, provisional filed 08/27/06, U.S. patent application filed 8/6/07.

  • I.J. Dmochowski, X. Tang, Photocleavable oligonucleotide and uses thereof, filed 12/04/06, provisional filed 11/27/07, U.S. patent application filed 11/08.

  • I.J. Dmochowski, P.A. Hill, Q. Wei, J.L. Chambers, Tri-functionalized cryptophanes and their use, provisional filed 07/07/08, U.S. patent application filed 7/07/09.

  • M. Jimbo, G. Robbins, N. Kamat, I.J. Dmochowski, M.J. Therien, D. Hammer, Polymer vesicles for selective electromagnetic energy-induced delivery, U.S. patent application #12/548,801 filed 8/27/09.